Advanced Parkinson's Disease Specialists in London

Living with any form of Parkinson’s Disease can have a serious impact on your life and the lives of your loved ones. Advanced Parkinson’s Disease requires particular attention as it is more difficult to live with the symptoms. At Dementech, we provide professional medical support and strive to provide an exceptional standard of care. Receive the support that you need to cope with your symptoms from our experts.

Neurologists in London

What is Advanced Parkinson’s Disease?

Advanced Parkinson’s Disease (APD) is quite simply the later stage of the disease. APD is characterised by limited mobility and several other symptoms. People with Parkinson’s Disease (PD) will usually develop APD after around 10 years, but this can vary depending on the individual.


At Dementech Neurosciences, we are at the forefront of our understanding of PD and we use cutting-edge technology – CANTAB – to assess the severity of cognitive deficits in patients with Parkinson’s Disease and APD. This helps us to provide an early diagnosis of cognitive impairment and outline the best treatment options to manage the condition.


Dementech is a private clinic based in London, specialising in the treatment of Parkinson’s. If you or a family member needs specialist treatment for Advanced Parkinson’s Disease, please contact us and we will be happy to provide any support you need.

Advanced Parkinson’s Disease Diagnosis & Treatment At Dementech

Advanced PD & Clinical Uncertain Parkinson’s patients can pose a diagnostic challenge, but our experts have years of experience across all facets of this complex disease. At Dementech, we’re confident in being among the best-placed specialists to help you achieve an accurate diagnosis and receive appropriate support throughout your treatment.


As PD advances to become APD, naturally, the symptoms will become more complex, although they will still vary depending on the individual. For example, patients may develop levodopa-induced postsynaptic dysregulation of striatal dopamine receptors. This would therefore require a slightly different and more complex approach to treatment, which we can facilitate.


Continuous dopaminergic stimulation is a novel therapeutic strategy for the management of Parkinson’s disease, which proposes dopaminergic agents that provide continuous stimulation of striatal dopamine receptors that will delay or prevent the onset of levodopa-related motor complications. However, pulsatile stimulation of dopamine receptors can also occur at this stage of APD. This pulsatile stimulation then leads to molecular and physiologic changes in basal ganglia neurons and the development of motor complications. These effects are reduced or avoided when dopaminergic therapies are delivered in a more continuous and physiological manner.


Most innovative, neoteric treatment strategies that provide continuous dopaminergic stimulation can be achieved with triple ‘P’ treatment in the form of a transdermal patch, pump, and continuous infusion therapies to help combat this debilitating and denervating illness.


At Dementech Neurosciences, we are delighted to be able to offer these advanced and novel treatment strategies to patients with Advanced Parkinson’s, under the supervision of our esteemed neurologist Professor Ray Chaudhuri. We follow stringent NICE guidelines and offer bespoke service and one-stop treatment.

Technology Used For Advanced Parkinson’s Disease

Dementech is committed to using the latest and most advanced testing methods for APD. To that end, we collaborate with famous universities and medical organisations for the development of new testing methods and experimental treatments. We use a combination of testing methods to establish an accurate diagnosis for Parkinson’s Disease and Advanced Parkinson’s Disease.


One of the most effective surgeries used for APD is Deep Brain Stimulation (DBS) surgery, whereby electrodes are inserted into the brain using Magnetic Resonance Imaging (MRI) to record brain activity during the procedure. This process has been proven to help patients manage their tremors, but it does pose some risks. Our specialists will be sure to keep every patient and their families aware of any potential risks or side effects before going ahead with any form of treatment.

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    Speak to a Parkinson's Disease Specialist

    0203 848 4500

    Dementech Neurosciences are London's leading neurological clinic specialising in advanced neurological conditions such as Vascular Dementia. Book a call with our clinic to speak to a specialist on your condition.

    Why Choose Dementech For Advanced Parkinson’s Disease Treatment?

    When facing the challenges of Parkinsonian Dementia, making informed decisions about your healthcare becomes paramount. In this endeavour, Dementech stands as a beacon of excellence in the field of neurodegenerative disorders. Our commitment to providing world-class care is underpinned by a team of specialists at the forefront of our field, armed with industry-leading technology that ensures swift and precise diagnoses, often with results available within just 48 hours.


    At Dementech, we understand the urgency of your needs, offering same-week consultations and assessments to expedite your journey toward effective treatment. With prices starting at £485, we are dedicated to making our services accessible. What truly sets us apart, however, is our holistic approach, as our Patient Advisors craft unique treatment plans and provide invaluable guidance following your consultation. Our commitment doesn’t end there; we offer ongoing support not only for patients but also for their families, recognising the vital role they play in the journey towards managing Parkinsonian Dementia. Discover why Dementech is your trusted partner in navigating the complexities of Parkinsonian Dementia, as we stand alongside you every step of the way.


    1. Home to the UK’s leading Advanced Parkinson’s Disease specialists
    2. Industry-leading technology provides a fast and accurate diagnosis, with results available in 48 hours
    3. Same week consultations and assessments
    4. Prices starting at £485
    5. Patient Advisors provide unique treatment plans and advice following your consultation
    6. Ongoing support for patients and their families

    Dr Kish Mankad

    Group 1808
    It was very useful to be able to talk with the consultant and be understood. My problem has been lifelong and got far worse over recent years. It was vital for me to be able to get advice and guidance and find a new treatment plan

    Patient Success Stories

    Dementech Neurosciences prides itself on delivering exceptional patient care. Here are just some of our patient testimonials.

    P Allen

    Group 180822

    “My family and I experienced one of the hardest times of our lives having to deal with my wife’s deteriorating condition. I would like to personally thank the lovely young lady Zobiaa from Dementech, for showering us with compassion, empathy and genuine care and concern. Her professionalism, high-level customer service and communication, eye for detail, and willingness to go the extra mile to accommodate our needs and make not only my wife, but our whole family, feel as comfortable and supported as possible, is something we will always be grateful for. Thank you so much for your friendly and polite presence Zobiaa and taking the time and effort to build a relationship with us. You really made our visits to the clinic a positive, 5 star experience.”


    Group 180822

    “Dementech Neurosciences is a relatively new clinic specialising in the scientific assessment and treatment of Parkinson’s Disease. It represents a significant development in the treatment of Parkinson’s and has done a great job of establishing itself and its reputation in a short period of time. The premises are extremely well situated in central London, the consultant neurologists are all at the top of their field in their specialisation of the treatment of Parkinson’s Disease, and the clinical and administrative staff are of a similar standard. The atmosphere of the clinic is positive and the results, in the short period of time I have been able to assess, have been similarly positive.”

    N Mohammed

    Group 180822

    “Have had nothing but kindness and professionalism from Dementech and all their staff. From their initial guidance by Shakeela, through to staff conducting the MRI tests and Dr. Lucio D’Anna for his expertise clarity of explanation, compassion and consideration. Special mention to Zobia, who saved the day with her quick thinking that helped my mother-in-law to obtain extended care. Overall a perfect experience. Cannot recommend them enough.”

    Discover More About Parkinson’s Disease

    Dementech Neurosciences is proud to deliver a high-standard diagnosis, as well as specialist treatment and ongoing support for patients suffering with PD at any stage of its progression. We strongly believe that prevention strategies can make a significant difference during the earlier stages, which is why we advise anyone experiencing mild symptoms, or with a family history of PD, to seek a professional diagnosis as soon as possible.

    To learn more about earlier stages of Parkinson’s Disease and how we can offer professional support, click here to view our Parkinson’s Disease Page. Read on to learn more about Advanced Parkinson’s Disease.

    J Adams

    Group 1808

    A pleasure to have the expertise, vision & support of Dementech, most especially the care and trust of Dr. D’Anna, Anca and the team!

    Meet Our Specialists

    London is home to a distinguished group of leading specialists in end-stage parkinsons, who enjoy global recognition for their expertise in this field. These specialists are at the forefront of pioneering research, diagnosis, and treatment of advanced Parkinson’s Disease, demonstrating an unwavering commitment to enhancing the lives of patients. Their extensive clinical experience, coupled with access to state-of-the-art medical facilities and resources here at Dementech, enables them to deliver comprehensive care and innovative therapies tailored to the unique needs of each patient. Whether it’s advancing our understanding of Parkinson’s through groundbreaking research or providing personalised treatment plans that improve the quality of life for patients, London’s Neurology specialists are renowned for their dedication to tackling this complex neurological condition.

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    About Dementech

    At our core, we are dedicated to enhancing your quality of life and overall well-being by delivering the highest standard of care. Recognising the need for a private centre that offers a holistic, multidisciplinary approach, we’ve embarked on a mission to transform the lives of individuals facing neurological disorders.


    Our commitment to this mission is fueled by the integration of cutting-edge technologies and advanced diagnostic methods, some of which are considered the best in the world. Although many of the neurological disorders we specialise in remain incurable, our focus on medication and other therapeutic modalities can effectively slow down disease progression and bring about substantial improvements in the patient’s quality of life.

    Contact Dementech

    Take the first step towards a better quality of life – contact our clinic today.

    Call us on 0203 848 4500