Advanced PD & Clinical Uncertain Parkinson’s patients can pose a diagnostic challenge to treating clinicians, and as the disease advances & high intermittent oral doses, pulsatile treatment of levodopa induce postsynaptic dysregulation of striatal dopamine receptors. This pulsatile stimulation leads to molecular and physiologic changes in basal ganglia neurons and the development of motor complications. These effects are reduced or avoided when dopaminergic therapies are delivered in a more continuous and physiologic manner.
Tripple ‘P’ Approach – Patch, Pipe & Pump for Parkinson’s
Continuous dopaminergic stimulation is a novel therapeutic strategy for the management of Parkinson’s disease, which proposes that dopaminergic agents that provide continuous stimulation of striatal dopamine receptors will delay or prevent the onset of levodopa-related motor complications. Most innovative, neoteric treatment strategies that provide continuous dopaminergic stimulation can be achieved with triple ‘P’ treatment in the form of a transdermal patch, pump and continuous infusion therapies help to combat this debilitating and denervating illness.
We are delighted to offer these advanced & novel treatment strategies to patients with Advanced Parkinson’s under the supervision of our esteemed neurologists Professor Ray Chaudhuri & Dr Vinod Metta. We follow stringent NICE guidelines and offer bespoke service and one-stop treatment.